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采用生物合成，经FPLC纯化，我们可提供高纯度的靶点特异性强的siRNA，并可按客户需求定制不同长度、不同形式的siRNA。 1) Zhang QY, Ho PY, Tu MJ, Jilek JL, Chen QX, Zeng S, Yu AM, Lipidation of polyethylenimine-based polyplex increases serum stability of bioengineered RNAi agents and offers more consistent tumoral gene knockdown in vivo, Int J Pharm. 2018 Aug 25;547(1-2):537-544. 2) Ponchon L, Beauvais G, Nonin-Lecomte S, et al. A generic protocol for the expression and purification of recombinant RNA in Escherichia coli using a tRNA scaffold[J]. Nature Protocols, 2009, 4(6):947-959 3) Ponchon L, Dardel F. Recombinant RNA technology: the tRNA scaffold.[J]. Nature Methods, 2007, 4(7):571-576. |